People have used various techniques from yoga and meditation to chanting, self discovery satsangs, and ecstatic dance. Anything that works to quiet the mind and its anxiety-generating mechanisms will lead to discovering and uncovering the soul. Then you will feel the profound peace that underlies all this turmoil.
Dulling the mind with substances is not the path because they do not weaken the chattering mind, they only paralyze it temporarily. The only way that is lasting is to weaken the monkey-mind by overriding it, allowing it to carry on, as you dive deeper into the profound peace that underlies it all.
Recognize that thoughts and feelings come and go, bodies and minds come and go. They do not last. What lasts is the soul. Allow yourself to feel this and you will want to live in it. Only things that last are real. When you realize this, it becomes easier and easier to dwell in your soul and find the tranquility within.